Allergic granulomatosis also known as Eosinophilic granulomatosis with polyangiitis (EGPA, formerly Churg-Strauss Syndro...

Buerger's disease (thromboangiitis obliterans) is a rare disease of the arteries and veins in the arms and legs. In Buerger's disease, your blood vessels become inflamed, swell and can become blocked with blood clots (thrombi). This eventu...

Bullous pemphigoid is an uncommon skin disease characterized by tense blisters on the surface of the skin. Occasionally, the inner lining tissue of the mouth, nasal passages, or conjunctivae of the eyes (mucous membrane tissue) can be involved. Th...

Collagenous colitis is a rare digestive disorder that primarily affects females and typically becomes apparent during middle age. The disorder is characterized by inflammatory changes of the mucous membranes (mucosa) of the colon (colitis) and abn...

Ulcerative colitis (UL-sur-uh-tiv koe-LIE-tis) is an inflammatory bowel disease ...

Ulcerative colitis (UL-sur-uh-tiv koe-LIE-tis) is an inflammatory bowel disease (IBD) that causes inflammation and ulcers (sores) in your digestive tract. Ulcerative colitis affects the innermost lining of your large intestine (colon) and rectum. ...

Mixed connective tissue disease facts Connective tissues are the framework of the cells of the body. Mixed connective tissue disease is an "overlap" combination of connective tissue diseases. Diagnosis of mixed c...

Mixed cryoglobulinemia is a rare disorder characterized by the presence of cryoglobulins in the blood. Cryoglobulins are abnormal proteins that thicken and clump together at cold temperatures, usually below 98.6 degrees Fahrenheit (the average hum...

Neuropathy is damage to nerves, and diabetic neuropathy is damage to nerves that occurs as a result of diabetes. Diabetes is thought to damage nerves as a result of prolonged elevated levels of blood glucose. Diabetic neuropathy can affect differe...

Though ulcers often heal on their own, you shouldn't ignore their warning signs. If not properly treated, ulcers can lead to serious health problems, including: Bleeding Perforation (a hole through the wall of the stomach)...

Genital herpes, also known as herpes simplex virus type 2 (HSV-2), is a sexually transmitted infection that causes painful sores and blisters on the genital area. It is a chronic condition that can flare up periodically, causing symptoms such as i...

Hand, Foot, and Mouth Disease (HFMD) is a common viral illness that usually affects infants and children under the age of 5, although it can also occur in older children and adults. It is caused by several different viruses, most commonly the coxs...

Herpangina facts Herpangina is a self-limited infection primarily caused by coxsackieviruses. Herpangina most often affects young children. Herpangina is associated with fever, sore throat, and blisters in the ba...

Herpetic gingivostomatitis is a viral infection caused by the herpes simplex virus. It is characterized by painful sores and ulcers in the mouth and on the gums, as well as fever, swollen lymph nodes, and general malaise. It is a common infection ...

High blood sugar (hyperglycemia) affects people who have diabetes. Several facto...

Impetigo facts Impetigo is a bacterial infection of the surface of the skin. Impetigo is more common in children than in adults. The two types of impetigo are non-bullous and bullous impetigo. Impetigo ...

Until recently the relationship of Stevens-Johnson syndrome to other severe blistering disorders was a matter of some debate. Now a consensus seems to be evolving that describes SJS as a rare disorder involving lesions of the mucous membranes alon...

Lichen planus facts Lichen planus is a chronic recurrent rash of unknown cause with no established cure. Lichen planus generally affects adults and can involve any portion of the body, but it has a predilection for the wri...

Lichen Planus is a rare, recurrent, itchy rash or area of inflammatory eruptions (lesions) of unknown origin characterized by shiny reddish-purple spots on the skin and gray-white ones in the mouth. The disorder may present as itchy spots on the w...

Oral cancer is a type of cancer that develops in the tissues of the mouth or throat. It can occur in the lips, tongue, gums, floor of the mouth, roof of the mouth, or the inner lining of the cheeks and throat. Oral cancer is often linked to tobacc...

Oral lichen planus is a chronic inflammatory condition that affects the mucous membranes inside the mouth. It is characterized by the presence of white, lacy patches or sores on the inside of the cheeks, gums, tongue, and other areas of the mouth....

The sarcoid of boeck (sarcoidosis) is a chronic inflammatory disease that can affect any organ in the body, but most often involves the skin and lungs.  Sarcoid of boeck is characterized by the formation of small, round bumps (...

Scabies is a highly contagious skin infestation caused by the microscopic mite Sarcoptes scabiei. It is characterized by intense itching and a pimple-like rash. Scabies is usually spread through close physical contact with an infected person, and ...

Scleroderma is a chronic autoimmune disease that causes the skin and connective tissues to become thickened and hardened. Oral scleroderma specifically refers to the involvement of the mouth and oral cavity in the disease. This can manifest as tig...

Billions of people worldwide carry the Staphylococcus aureus bacteria, but most are unaffected by it. There are more than 30 different types of bacteria that are classified as Staphylococcus; the most common is Staphylococcus aureus. ...

Cutis marmorata telangiectatica congenita (CMTC) is a rare inherited disorder characterized by discolored patches of skin caused by widened (dilated) surface blood vessels. As a result, the skin has a purple or blue "marbled" or "fishnet" appearan...