ANK3-related intellectual disability-sleep disturbance syndrome is a rare genetic disorder caused by mutations in the ANK3 gene. It is characterized by intellectual disability, sleep disturbances, and other neurological features such as seizures, ...

Ankyloblepharon filiforme adnatum-cleft palate syndrome (AFA-CP) is a rare genetic disorder characterized by the fusion of the eyelids, cleft palate, and other facial abnormalities. It is caused by a mutation in the TP63 gene, which is responsible...

Ankyloblepharon filiforme adnatum-imperforate anus syndrome (AFA-IA) is a rare genetic disorder characterized by the fusion of the eyelids, imperforate anus, and other physical anomalies. It is caused by a mutation in the TP63 gene. Symptoms may i...

Ankyloblepharon-ectodermal defects-cleft lip/palate syndrome (AEC syndrome) is a rare genetic disorder characterized by the presence of ankyloblepharon (fusion of the eyelids), ectodermal defects (abnormalities of the skin, hair, nails, and teeth)...

Ankyloglossia, also known as tongue-tie, is a condition in which the lingual frenulum (the band of tissue that connects the bottom of the tongue to the floor of the mouth) is shorter than normal, restricting the movement of the tongue. This can ca...

Ankylosing spondylitis facts Ankylosing spondylitis belongs to a group of arthritis conditions that tend to cause chronic inflammation of the spine (spondyloarthropathies). Ankylosing spondylitis affects males two to three...

Ankylosing vertebral hyperostosis with tylosis is a rare condition that affects the spine and can cause the vertebrae to fuse together. It is characterized by the formation of bone spurs (osteophytes) on the vertebrae, which can lead to a narrowin...

Ankylostomiasis, also known as hookworm infection, is a parasitic infection caused by two species of hookworms, Ancylostoma duodenale and Necator americanus. It is most commonly found in tropical and subtropical regions, and is spread through cont...

Annular atrophic lichen planus is a rare form of lichen planus, a chronic skin condition that causes an itchy, scaly rash. It is characterized by round, atrophic (thinned) patches of skin with a raised, scaly border. The rash may be red, purple, o...

Annular epidermolytic ichthyosis is a rare genetic skin disorder that is characterized by thick, scaly patches of skin that form on the body. The patches are usually red and may be itchy or painful. The condition is caused by a mutation in the ker...

Annular lichen planus is a type of skin condition that is characterized by raised, scaly, and itchy patches on the skin. It is caused by an autoimmune reaction, and it can affect any area of the body, including the scalp, nails, and mucous membran...

Anoctamin-5-related limb-girdle muscular dystrophy R12 is a rare, inherited disorder that affects the muscles. It is caused by mutations in the ANO5 gene, which is responsible for producing anoctamin-5, a protein involved in muscle contraction. Sy...

Anodontia is a rare condition in which a person is born without any teeth. It is a congenital disorder, meaning it is present at birth. People with anodontia may have difficulty eating and speaking, and may require dentures or other dental prosthe...

Anodontia is a rare genetic disorder characterized by the complete absence of teeth. It can affect both primary (baby) teeth and permanent teeth. Anodontia can be either isolated, meaning it occurs on its own, or it can be part of a syndrome that ...

Anomalous aortic origin of the left coronary artery (AAOLCA) is a rare congenital heart defect in which the left coronary artery arises from the aorta instead of the pulmonary artery. This can lead to decreased blood flow to the left side of the h...

Anomalous aortic origin of the right coronary artery (AAORCA) is a rare congenital heart defect in which the right coronary artery originates from the aorta instead of the left coronary artery. This can lead to decreased blood flow to the right si...

Anomalous origin of coronary artery from the pulmonary artery (AOCA) is a rare congenital heart defect in which one of the coronary arteries arises from the pulmonary artery instead of the aorta. This can lead to decreased blood flow to the heart ...